One of the challenges in mathematical biology is to find an underlying code in the structure of DNA. Researchers from the State University of Campinas, Brazil, have demonstrated the existence of error-correcting codes associated with DNA sequences.
As well as having applications in protein engineering, these results may shed light on the evolution of genes and genomes.
DNA sequences generated by BCH codes over GF(4)
Electron. Lett. -- 4 February 2010 -- Volume 46, Issue 3, p.202–203
L.C.B. Faria (1), A.S.L. Rocha (1), J.H. Kleinschmidt (1), R. Palazzo, Jr (1) and M.C. Silva-Filho (2)
(1) State University of Campinas, Department of Telematics, School of Electrical and Computer Engineering, Brazil
(2) University of Sao Paulo, Department of Genetics, Luiz de Queiroz College of Agriculture, Brazil
The question raised by researchers in the field of mathematical biology regarding the existence of error-correcting codes in the structure of the DNA sequences is answered positively. It is shown, for the first time, that DNA sequences such as proteins, targeting sequences and internal sequences are identified as codewords of BCH codes over Galois fields.
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